FAQ About Xiangqun Xie

• What is Xiangqun Xie's address?

  Xiangqun Xie is located at
  Pittsburgh, Pennsylvania, United States

• What is Xiangqun Xie's job title?

  Xiangqun Xie is a As Associate Dean for Research Innovation, I have provided my visionary leadership and innovation strategy, and have successfully led several research and teaching program. I have also served as a Charter Member of the Science Advisory Board to the US FDA. As Director/PI, I have led an NIH-funded Center of Excellence, a joint initiative between University of Pittsburgh and Carnegie Mellon University by creating fruitful collaborations that catalyze interdisciplinary research in the greater Pittsburgh area and beyond. As PI/Professor of an integrated MediChemBiology Lab, I have developed an AI computational drug design and discovery technology with over 190 publications in CELL, Nat. Comm, PNAS, JMC journals. I was co-PI/Core Director on three NIH center grants (P50 PCMLD, U54 PMLSC and NCI/SAIC). As Founder Director of Pharmacometrics Systems Pharmacology (PSP) program, I have developed a new education and research training program for data science-driven PSP preclinical and clinical pharmacoanalytics. Overall, I have brought my expertise in machine-/deep-learning (ML/DL) chemogenomics systems pharmacology and medicinal chemistry drug design discovery into the cutting-edge translational R&D as well as clinical data mining pharmacoanalytics. As proof of our developed technologies above, I have published: i) 3D cryo-EM structure of cannabinoid receptor CB2/Gi signaling complex (Cell, 2020) and discovery of novel CB2 agonists, inverse agonists, neutral antagonists and allosteric modulators with therapeutic potential for cocaine-attenuation, kidney fibrosis and osteoporosis (5 patents, 3 JMC, 2 PNAS and Kidney Int.); ii) First-in-class p62-ZZ drug molecules (global patents and Leukemia 2016, Nat Comm 2017, PNAS 2018); iii) First INK4C/p18-targeted drug (patent, 2015) for ex vivo expansion of murine and human hematopoietic stem cells (HSC) (Nat Comm 2015 and Sci Reports 2015); and iv) the first on Nature Scientific Report about cardiovascular disease-specific chemogenomics knowledgebase-guided target identification and drug synergy mechanism study of a combination of herbal medications "Sini Decoction" (四逆汤). I am also a recipient of AAPS Award for Outstanding Research Achievements.

• What industry does Xiangqun Xie currently work in?

  Xiangqun Xie currently works in the University Of Pittsburgh School Of Pharmacy | University Of Pittsburgh |

• Which languages does Xiangqun Xie speak?

  No Languages Available

• Which industries has Xiangqun Xie previously worked in?

  Xiangqun Xie has prior
  experience in the following industries:
  University Of Houston College Of Pharmacy | University Of Connecticut

• What is Xiangqun Xie’s work experience?

  Xiangqun Xie has the following professional experience:
  University Of Pittsburgh School Of Pharmacy | University Of Pittsburgh | University Of Houston College Of Pharmacy | University Of Connecticut

• How can I find Xiangqun Xie on LinkedIn?

  You can view Xiangqun Xie’s LinkedIn profile at LinkedIn URL

• What are Xiangqun Xie’s work email addresses?

  Xiangqun Xie’s work email
  addresses are
  xiangqun.xie@pitt.edu

• What company does Xiangqun Xie work for?

  University Of Pittsburgh School Of Pharmacy | University Of Pittsburgh |