Pat Brady Email & Phone Number | Self-driven computational scientist and action-oriented doer with 20+ years of pharma experience defining data & computational strategy, developing custom computational infrastructure and directly impacting therapeutic programs • Led a small team of Ph.D. computational chemists for ~20 years to impact drug discovery via infrastructure development & applied computation and analytics • Led the Screening Analytics SIG in GSK for 14 years and coordinated analytics support for the global HTS portfolio • Led an educational program in GSK that has provided pragmatic data science training to hundreds of Discovery scientists over 6 years • Provided direct computational support for over 50 therapeutic projects in hit identification, hit to lead, and lead optimization phases • Developed and deployed dozens of custom cheminformatics and computational chemistry domain-focused applications in support of drug discovery programs and initiatives in GSK Full CV available upon request Comp Sci Expertise: Analytics automation; biological fingerprints & target/assay clustering; chemical clustering & diversity sampling; cheminformatics, data acquisition & manipulation; data visualization; hit triage; library enumeration & multi-objective combinatorial library design; molecular docking; molecular superposition; pharmacophore fingerprints; protein binding site mapping; relational databases (oracle, mysql, dbm); scientific software development; software engineering & web deployment; screening analytics (HTS, ASMS, DEL, FBS, CETSA); structure-based design; teaching & hands-on data science instruction; virtual screening for scaffold hopping (3D & 2D) and SAR hit expansion (2D) Software: Tibco Spotfire (visualization); RDKIT; CCG software (MOE, Pharmacophore searching); OpenEye tools (FastROCS/ROCS, Omega, OEChem); Chemaxon tools; Schrodinger software (Maestro, Glide). Languages: python, perl, c++/c, php, SQL (mysql, oracle), CUDA (c) Systems: Fluent in unix (linux, irix) and windows operating systems; experienced in cpu/gpu cluster computing & queueing (slurm, sge, & lsf queuing)

Pat Brady

Self-driven computational scientist and action-oriented doer with 20+ years of pharma experience def...
Collegeville, Pennsylvania, United States

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Pat Brady’s Email pbrady@kymeratx.com

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Pat Brady’s Location Collegeville, Pennsylvania, United States

Pat Brady’s Current Industry Kymera Therapeutics

Pat Brady’s Prior Industry Gsk | Bristol Myers Squibb | Dupont Pharmaceuticals | Dupont Merck Pharmaceutical

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Work Experience

Kymera Therapeutics

Senior Director, Computational Chemistry

2022-06-01 00:00:00 - Present

Gsk

Associate Director

2021-12-01 00:00:00 - 2022-06-01 00:00:00

Bristol Myers Squibb

Senior Research Investigator

2001-10-01 00:00:00 - 2002-11-01 00:00:00

Dupont Pharmaceuticals

Senior Research Scientist

1999-07-01 00:00:00 - 2001-10-01 00:00:00

Dupont Merck Pharmaceutical

Postdoctoral Scientist

1997-08-01 00:00:00 - 1998-07-01 00:00:00

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FAQ About Pat Brady

Pat Brady is located at
Collegeville, Pennsylvania, United States

Pat Brady is a Self-driven computational scientist and action-oriented doer with 20+ years of pharma experience defining data & computational strategy, developing custom computational infrastructure and directly impacting therapeutic programs • Led a small team of Ph.D. computational chemists for ~20 years to impact drug discovery via infrastructure development & applied computation and analytics • Led the Screening Analytics SIG in GSK for 14 years and coordinated analytics support for the global HTS portfolio • Led an educational program in GSK that has provided pragmatic data science training to hundreds of Discovery scientists over 6 years • Provided direct computational support for over 50 therapeutic projects in hit identification, hit to lead, and lead optimization phases • Developed and deployed dozens of custom cheminformatics and computational chemistry domain-focused applications in support of drug discovery programs and initiatives in GSK Full CV available upon request Comp Sci Expertise: Analytics automation; biological fingerprints & target/assay clustering; chemical clustering & diversity sampling; cheminformatics, data acquisition & manipulation; data visualization; hit triage; library enumeration & multi-objective combinatorial library design; molecular docking; molecular superposition; pharmacophore fingerprints; protein binding site mapping; relational databases (oracle, mysql, dbm); scientific software development; software engineering & web deployment; screening analytics (HTS, ASMS, DEL, FBS, CETSA); structure-based design; teaching & hands-on data science instruction; virtual screening for scaffold hopping (3D & 2D) and SAR hit expansion (2D) Software: Tibco Spotfire (visualization); RDKIT; CCG software (MOE, Pharmacophore searching); OpenEye tools (FastROCS/ROCS, Omega, OEChem); Chemaxon tools; Schrodinger software (Maestro, Glide). Languages: python, perl, c++/c, php, SQL (mysql, oracle), CUDA (c) Systems: Fluent in unix (linux, irix) and windows operating systems; experienced in cpu/gpu cluster computing & queueing (slurm, sge, & lsf queuing)

Pat Brady currently works in the Kymera Therapeutics |

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Pat Brady has prior
experience in the following industries:
Gsk | Bristol Myers Squibb | Dupont Pharmaceuticals | Dupont Merck Pharmaceutical

Pat Brady has the following professional experience:
Kymera Therapeutics | Gsk | Bristol Myers Squibb | Dupont Pharmaceuticals | Dupont Merck Pharmaceutical