Helene Cousin Email & Phone Number | The formation of the face in vertebrate animals is a complex and precisely orchestrated process involving the sequential migration, proliferation and differentiation of a population of cells named the cranial neural crest cells (CNC). While the sequence of morphological events is highly conserved during the development of various vertebrate animals, there is tremendous plasticity in the timing and extent of these events. This plasticity is at the origin of the huge diversity of craniofacial features of these animals. However, the complexity of these events makes them also extremely vulnerable to endogenous or exogenous factors that can lead to craniofacial defects. In the United States, abnormal craniofacial development represents a third of all birth defects. The identification of the molecules involved in the craniofacial morphogenesis is key to understanding and preventing the emergence of these defects. Using the Xenopus model system, we aim to identify such molecules and elucidate their function. On june 14th, 2016, I was awarded an R03 grant from the NIH (R03 DE025692) to investigate the role of Lbh (Limb Bud and Heart) protein during craniofacial development of vertebrates. For more information, see the document attached below.

Helene Cousin

The formation of the face in vertebrate animals is a complex and precisely orchestrated process inv...
Amherst, Massachusetts, United States

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Helene Cousin’s Location Amherst, Massachusetts, United States

Helene Cousin’s Current Industry University Of Massachusetts Amherst

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2021-09-01 00:00:00 - Present

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2000-10-01 00:00:00 - 2003-09-01 00:00:00

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Helene Cousin is a The formation of the face in vertebrate animals is a complex and precisely orchestrated process involving the sequential migration, proliferation and differentiation of a population of cells named the cranial neural crest cells (CNC). While the sequence of morphological events is highly conserved during the development of various vertebrate animals, there is tremendous plasticity in the timing and extent of these events. This plasticity is at the origin of the huge diversity of craniofacial features of these animals. However, the complexity of these events makes them also extremely vulnerable to endogenous or exogenous factors that can lead to craniofacial defects. In the United States, abnormal craniofacial development represents a third of all birth defects. The identification of the molecules involved in the craniofacial morphogenesis is key to understanding and preventing the emergence of these defects. Using the Xenopus model system, we aim to identify such molecules and elucidate their function. On june 14th, 2016, I was awarded an R03 grant from the NIH (R03 DE025692) to investigate the role of Lbh (Limb Bud and Heart) protein during craniofacial development of vertebrates. For more information, see the document attached below.